| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5161f961b768730987d5591474eb8d44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a05a4c69e4566ad2fab1d9f0a23cd2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa45225022a93501d121676079efd2fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_097580da9593b453337937ae513c119b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-773
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-915
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-923
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-40 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0671
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
| filingDate |
2011-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64bdcccd814625749e9a39e753182a08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60d49bc3115c02338078e989d934589d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35e209899af85f0bd60fce4271abd5e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e7943c132e64328a10dcf64e61bccb6 |
| publicationDate |
2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8852614-B2 |
| titleOfInvention |
Hydrogels with network defects enhanced by nanoparticle incorporation |
| abstract |
Compositions and methods are provided for the manufacture and use of hydrogels with increased permeability to macromolecules with minimum loss of matrix mechanical strength and prepolymer viscosity for patternability. The hydrogels of the invention are formed from a prepolymer, which is polymerized in the presence of hydrophobic nanoparticles. In some embodiments of the invention cells are present during polymerization, and are encapsulated by the hydrogel. A high interfacial energy between the hydrophobic substrate and the aqueous polymerizing solution disrupts the hydrogel network structure, leading to network defects that increase permeability without loss of patternability. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10545075-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021178949-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11254974-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10495554-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10641782-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10746981-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11624685-B2 |
| priorityDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |