Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fcb093a174d5182b5854b704cb09354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f63eecb83c17f70b314aebe73e0f023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc98acc7b25db1fb35032bf5d2e2fd72 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2008-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0336de4b591e27562b0b42fe3333fe56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_796dc60b7028a6e757404eb93f639df8 |
publicationDate |
2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8846386-B2 |
titleOfInvention |
sVEGFR-2 and its role in lymphangiogenesis modulation |
abstract |
Disclosed herein are nucleic acid molecules comprising a nucleotide sequence of sVEGF-2, proteins encoded by those sequences and antibodies that bind to the protein. Also disclosed are methods for inhibiting or enhancing expression or activity of sVEGFR-2 and methods for inhibiting graft rejection, particularly cornea graph rejection. Also described are methods for inhibiting lymphangiogenesis and lymphatic endothelial cell proliferation by administering an effective amount of sVEGFR-2 and methods for treating lymphedema by inhibiting the activity of sVEGFR-2. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11702660-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11096956-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10538764-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10696969-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10683503-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10941405-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913947-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083745-B2 |
priorityDate |
2007-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |