Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60adc7403058c651192bdd20288cf4c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3383e2c931bd63baff0da0eabf80273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_292238d06bff193686994d989af4bd75 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6068 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2010-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8574c46c91429de2dc1e44fde9b1c527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1efb37f4280f72281569447e98140290 |
publicationDate |
2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8846342-B2 |
titleOfInvention |
Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells |
abstract |
The invention is directed to bioconjugate vaccines comprising N-glycosylated proteins. Further, the present invention is directed to a recombinant prokaryotic biosynthetic system comprising nucleic acids encoding an epimerase that synthesizes an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus. The invention is further directed to N-glycosylated proteins containing an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus and an expression system and methods for producing such N-glycosylated proteins. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015190492-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9764018-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020120569-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021255684-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014335127-A1 |
priorityDate |
2009-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |