Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da76440f91643f4d2aed4ed31d4cf17d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5021e64ccb40c87234b6a4b2512f3ccb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99fef01b5e3a4ea3210e63e386331788 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b69b308cae52ed241c3c9c7fb5aa395c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_647c385a6a6cc7d61b253751a171484f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate |
2010-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83aacb7cdf44ed52cc4aba459832c39c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f12e8c68232bd171fa39e40fb1de5c51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d75cfa8482bfa030d08aeb66e1ce3d13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe6cb4ccb94e58916535b6ea0472a421 |
publicationDate |
2014-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8841438-B2 |
titleOfInvention |
Trans-acting RNA switches |
abstract |
Disclosed are RNA constructs which function to activate or inactivate a biological process, e.g., may be designed for attachment to a polypeptide coding region. Such RNA constructs modulate translation of a polypeptide from the coding region in response to the presence of a target polynucleotide in an expression environment. Such RNA constructs include a weakened stem-loop structure which, when bound to the target polynucleotide, assumes stem-loop secondary structure and associates with an RNA binding protein. Association with the RNA binding protein modulates translation of the polypeptide coding region. Such RNA constructs also have three-way junction joining regions 3′ and 5′ of the stem-loop structure. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018079786-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9719085-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10466232-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11254935-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016149426-A1 |
priorityDate |
2009-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |