Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_624de03472ef3d6e44d2cc23bfa3c30c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_762b5e7716f77dd0f9648dfa843a6ff5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd3a34f912dd70643a3b25f09ab626ef |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2321-2041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0681 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-143 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D65-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-50255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F33-813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F13-1013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F33-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F13-0818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F33-452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F13-1022 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D65-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F13-08 |
filingDate |
2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_337139e13ada214912174ffb7dc666ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_124e527342c260c935991b4fd1cbeaf5 |
publicationDate |
2014-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8840849-B2 |
titleOfInvention |
Permeation device and method for reducing aqueous boundary layer thicknesses |
abstract |
The invention provides a permeation device ( 2 ) comprising a receiving vessel ( 6 ) having an aperture adapted for receiving an insert well ( 4 ). Both the vessel ( 6 ) and well ( 4 ) are used as either donor or acceptor compartments for permeability assays. The vessel ( 6 ) or well ( 4 ) comprises a porous suppor ( 8 )t, which may comprise biological or biomimetic materials, adapted for a molecular entity to permeate therethrough. In one embodiment, a stirring member ( 24 ) disposed in the vessel ( 6 ) can provide solution agitation to reduce aqueous boundary layer thickness adjacent to the support ( 8 ). Boundary layer thicknesses can be reduced by a device ( 2 ) of the invention to less than about 15 um such that a molecular entity permeating the support closely approximates in vivo absorption and transport conditions. |
priorityDate |
2004-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |