http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8835442-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4ba90e6dc688f187fe7f0e01a585a5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_daf993fdd4ffe428559c7941d80cdaf3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-00 |
| filingDate | 2010-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e2d75b0f1cc4ad348d8b19498cb5ccb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44ae8ff40a0fca95b204b6696c3ca1a9 |
| publicationDate | 2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8835442-B2 |
| titleOfInvention | 3-substituted 7-imino-2-thioxo-3, 7-dihydro-2H-thiazolo [4,5-di pyrimidin-6-yl—and process for preparation thereof |
| abstract | The present invention relates to novel 3-substituted (7-imino-2-thioxo-3,7-dihydro-2H-thiazolo[4,5-d]pyrimidin-6-yl of formula 1 wherein R is selected from a group consisting of hydrogen, alkyl having carbon no up to 10, allyl, cycloalkyl, aromatic, substituted aromatics (halogen, OH, COOH, OCH 3 , alkyl, etc), pyridyl, piperidine, piprazine, morphine. R 1 is selected from a group consisting of NH 2 , NHR, N(R) 2 (wherein R could be aliphatic or olefinic group up to 10 carbon), hetrocycles such as furan, thiophene, pyrole, prydyl, piprazine, morphine and R 2 is O and S separately. Particularly the present invention relates to (7-Imino-3-substituted-2-thioxo-3,7-dihydro-2H-thiazolo[4,5-d]pyrimidin-6-yl)-urea (15-21) and Furan-2-carboxylic acid (7-imino-3-substituted-2-thioxo-3,7-dihydro-2H-thiazolo[4,5-d]pyrimidin-6-yl)-amide. The compounds of present invention are useful in the treatment of central nervous disorders including, Parkinson disease, Huntington's disease, attention disorder, cognition, Alzheimer disease, depression and hypertension. |
| priorityDate | 2009-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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