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filingDate 2010-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0989769d8c887dac88e3f34c6746d640
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publicationDate 2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8835164-B2
titleOfInvention Cell line stably expressing mutated oncoprotein E6 and method of screening anticancer compound of uterine cervical cancer using the same
abstract Disclosed are a cell line that expresses protein of Seq. No. 1, and a method for screening an anticancer compound of uterine cervical cancer by using the same. The stable cell line that expresses oncoprotein E6 of a human papillomavirus type 16 variant strain is used to determine a difference in amounts of expression of tumor suppressor genes, such as p53, between E6 protein of the reference strain and E6 protein of a variant strain, thereby screening an anticancer compound of uterine cervical cancer, etc. Further, it is possible to develop an anticancer agent of uterine cervical cancer.
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