Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d0a0a8561c8adec8f8a460dbe9eb1d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5bd13be01b676f3acfafc151bce82b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08c507fab1aebee6198083e98a3e5ef1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D219-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C245-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-655 |
filingDate |
2011-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_792c736251d224fd8931fc677ac6f61a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96b9ad8bba5c8c2c761f8e70b5bf79ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21498c41a969593b0ad67daef64c9928 |
publicationDate |
2014-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8828976-B2 |
titleOfInvention |
Identification and use of compounds that affect the fidelity of eukaryotic translation initiation codon selection |
abstract |
A screening method for identifying compounds that alter the fidelity with which the initiation codon in mRNAs is recognized by the translational apparatus in eukaryotes is disclosed. This screening method was used to identify compounds having such activity. Methods of altering the fidelity of initiation codon selection are also disclosed. Methods of treating disorders characterized by single nucleotide mutations in initiation codons using compounds identified by the screening method, as well as methods of treating fungal and parasitic infections and hyperproliferative disorders using compounds identified by the screening method are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015025044-A1 |
priorityDate |
2010-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |