Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bf7439808d578ab8c3698f7560fe4ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbdc68ca0aa38fef2d059853ef2b31e6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2012-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9943bc060a5f9883d585358655320f19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7ec3f57a74306ef6ece87f43bd79a7b |
publicationDate |
2014-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8809275-B2 |
titleOfInvention |
Peptoids and methods for treating alzheimer's disease |
abstract |
Provided herein are peptoids capable of inhibiting or reversing amyloid β (Aβ) fibril or plaque production. The peptoids form a helical structure with three monomers per helical turn and have at least two monomers with a side-chain having an arylalkyl group having the same chirality positioned such that the side-chains are on the same side of the peptoid. Also provided are methods of using the peptoids to inhibit or reverse aggregation of Aβ and methods of treating subjects with Alzheimer's disease (AD) or slowing the progression of AD. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10167315-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11197908-B2 |
priorityDate |
2011-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |