Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e451da4bf67af46c1214f793d7763347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42a59c5faed1d0699d86edc5a2eee671 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6120cb4285bd394d75be98c50ed04f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97fdddb1c257c776090a14a347a98a34 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-74 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-41 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-62 |
filingDate |
2009-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8efaa35a21b4af37c669ac88f77b9fd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bfaf20a7db145b771fc42f2ba78f11a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8206adbd73220b9110d118035b821ef |
publicationDate |
2014-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8796491-B2 |
titleOfInvention |
Process for manufacturing adamantane derivatives with high yield |
abstract |
The present invention pertains to process for the amidation of a substituted 1-bromo-adamantane comprising a step (0) of reacting a substituted adamantane with an excess of bromine to obtain a 1-bromo-adamantane and a step (i) of reacting said substituted 1-bromo-adamantane with an amide, wherein the substituted 1-bromo-adamantane is used in the form of a mixture comprising bromine as obtained in step (0), wherein in step (0) a bromine: substituted adamantane molar ratio of from [2.5:1] to less than [5:1] is employed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4005565-A1 |
priorityDate |
2008-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |