Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1263f8210d30016749935caa917f4e1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7dffbd04747d5d9b9492e7f2ac61db6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cfcd7cb2f4a54b75c8a9e688182c539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cba42ffb28e8599c9918b40cb4f31ad0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
filingDate |
2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e2bf788f0606ab1ef66db625be7255d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_881ab31d8fd8c6353048e552ccd9deaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a8574edaec1b5ae90e6ba6618836fb1 |
publicationDate |
2014-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8785406-B2 |
titleOfInvention |
Stabilized and lyophilized formulation of anthracycline compounds |
abstract |
The present invention provides a lyophilized amrubicin formulation and a process thereof. In the process, the concentration of the aqueous solution before lyophilization is controlled to about 7.5 mg(potency)/mL or more. Thus, the formulation decreases the production of desaccharified compound and is stable to storage for a long period. The formulation is useful as a cancer chemotherapeutic agent. |
priorityDate |
2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |