| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b13a186c49b545a92867e3b9ed28213a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_134a9e77d22d33a235c17cd7e1cdb273
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d7dc95ac43b638567e1d5cbcad65f33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4bb2b15ee842821e2028150cbf93813 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate |
2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ab55ff8fd8c8c356d7195029e8788be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe69d2778575a6c0e50484a8055acfc4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a20e31afaaac46057ab66b5bb54ebce |
| publicationDate |
2014-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8778953-B2 |
| titleOfInvention |
Inhibitors of P38 map kinase |
| abstract |
Compounds of formula (I) are p38 MAP kinase inhibitors useful for the treatment of autoimmune and inflammatory diseases: wherein: G is —N═ or —CH═; D is an optionally substituted divalent mono- or bi-cyclic aryl or heteroaryl radical having 5-13 ring members; R6 is hydrogen or optionally substituted CrC3 alkyl; P represents hydrogen and U represents a radical of formula (IA); or U represents hydrogen and P represents a radical of formula (IA); wherein A represents an optionally substituted divalent mono- or bicyclic carbocyclic or heterocyclic radical having 5-13 ring members; z is O or 1; —X 1 -L 1 -Y— is a linker radical or bond; R 1 is a carboxylic acid group (—COOH), or an ester group which is hydrolysable by one or more intracellular esterase enzymes to a carboxylic acid group; and R 2 and R 3 are as defined in the claims. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9896417-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9388136-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10370332-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11382902-B2 |
| priorityDate |
2008-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |