http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8764697-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c12ca0ac917b4a40930bf58c4ff0d5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c17b15868227c630f0351e5cf5d1973 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y80-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M27-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M5-00 |
| filingDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fb8c6ca5b736b24cf9b5fcc108de0bf |
| publicationDate | 2014-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8764697-B2 |
| titleOfInvention | Systems and methods for an advanced medical device |
| abstract | The present invention relates to a biologically active medical device, which includes a matrix seeded with progenitor cells, and then covered by ciliated tissue. The matrix is capable of enabling cellular migration. The ciliated tissue is ependymal cells that express at least one of tight junctional complexes, zonula adherens, and gap junctions. The progenitor cells include subpendymal progenitor cells. In some cases the progenitor cells include stem cells, and the ciliated tissue includes at least one of Choroid cells, tanacytes, and circumventricular organs. In some embodiments, the medical device is oriented into a tubular structure in order to form a cerebrospinal shunt. Additional cells and structures may be imbedded within the matrix, such as glia, endothelial cells, stem cells, and blood vessels. The medical device may also be incorporated into a bioreactor including a flexible inner tube defining an anthropomorphically shaped lumen. |
| priorityDate | 2006-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.