Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba353b8a64ba073e844ddb7e1e7a528a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47a90307a1e75f2fe35ae3c961bab916 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_788af2972cf012c4cec55dee8ca5da54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d9b74b4e53b5e0d8ba7157beb5a9de3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaacf277d1ca555b6a99ad72dec179b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b2299c0b957d9f5ab969e92f599cd79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3f6719c43d23b3f128b1932319f31f9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C55-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-64 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-00 |
filingDate |
2009-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f90ca24ce40489affa38e303dfdf7bbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0693c3cbc4ade3defb760389feed8c77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbcb58b395283f02c6a36995b00b3a48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f1bb0f73e4bd34dda1921853b547aef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23fcad2f525da917db91ebe0042c84c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cec1a89378ab18e1b7ce2a167c9a816 |
publicationDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8754261-B2 |
titleOfInvention |
Process for the preparation of O-desmethyl-venlafaxine and salts thereof |
abstract |
The present invention relates to a novel process for the preparation of O-desmethyl venlafaxine (ODV) and the pharmaceutically acceptable salts thereof, wherein it comprises (i) provision of spiro-venlafaxine compound as intermediate; (ii) conversion of spiro-venlafaxine intermediate into ODV free base in a one-pot process; and (iii) optionally conversion ODV free base into pharmaceutically acceptable salts. The present invention further relates to novel processes for the preparation of crystalline salts of ODV-succinate and ODV-oxalate. |
priorityDate |
2009-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |