Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e9388ca3e5431ed56eaea044822383a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_72d4aac0257a74d5f1552051d4ed001c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84891e6d7e8934de7116f2082a61ae44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adef6d304637224dba7c80d8ed1906f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdf7b8916345b671dbfd9676e6b00021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed1da837290aa30f39cf66f98858ce96 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-50 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-84 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-04 |
filingDate |
2008-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba32b45d466ebfca6e1fbf123b740abe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_939df44bf157c394ed02c1ee791bed56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9300130febe209be21025aa74aceeb56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_802760d31522709083b5ba12e09e2402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a121df04284d015c1e7bdeaf76f9e52 |
publicationDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8753856-B2 |
titleOfInvention |
Stable biocatalysts of penicillin acylase as gel aggregates and the process of manufacture thereof |
abstract |
The present invention provides a stable and viable biocatalyst with high activity and operational stability and method of immobilization thereof. The immobilization process is based on the principle of entrapment of partially purified enzyme precipitate which is simultaneously aggregated by cross linking agent like glutaraldehyde and further entrapped in a combination of natural polymer like gelatin and synthetic polymer like polyvinyl alcohol with effective gelation under mild conditions of temperature and pH, resulting in a stable biocatalyst. The enzymes immobilized by the above process include Penicillin acylase from r E. coli RE III (pKA18), Novel Penicillin acylase from Achromobacter sp (CCM4834) expressed in r E. coli BL21 (pK1P1) CCM 7394 and r E. coli RE III (pKX1P1). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108603177-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108603177-A |
priorityDate |
2008-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |