Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d9846dcc334294aa16d5badd06161b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4528b3a904fc6e1c431b4f26cc31e2a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7739e20c66b28d34d782ac0c361255e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D1-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108 |
filingDate |
2013-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2c8c5f27993c85e56a057d3093d1e22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e78ede492784f88f946490047529145 |
publicationDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8753643-B1 |
titleOfInvention |
Spray dried compositions and methods of use |
abstract |
Provided herein are insoluble particles that include polypeptides. The polypeptides may have immunogenicity that is greater than the immunogenicity of the same polypeptides when they are not present in the particle. The polypeptides may be soluble before incorporation into the particles and insoluble after incorporation into the particles. The particles may include lipopolysaccharide, wherein the lipopolysaccharide is insoluble. The particles may include a carrier. In one embodiment, a carrier is present at no greater than 0.001 mg carrier/mg particles. In one embodiment, a carrier is present at a ratio of carrier to polypeptide (weight:weight) of no greater than 0.05:1. In one embodiment, a carrier is not detectable in the particles. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11090622-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10569244-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10850244-B2 |
priorityDate |
2012-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |