Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5afb8c43e880192d7e8f455a9becff71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7797fadff68d537c70da7bfdd36b61c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f49cef3f60a9ebccf6a8fb5f650f2023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc501f9e376fbed2c848e43c79b17efa |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-02 |
filingDate |
2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f3cd38d29f541798138fe03834dd729 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5acd431186fb52ddb236e1f480f2f8e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e14358528cb978df13a4ba797b16ef4a |
publicationDate |
2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8748497-B2 |
titleOfInvention |
Optimized fluorocarbon emulsions for blood substitutes and other therapeutic uses |
abstract |
The present invention is directed to a stable fluorocarbon emulsion having a continuous aqueous phase and discontinuous fluorocarbon phase comprising two fluorocarbons and surprisingly demonstrates that perfluorodecyl bromide is as effective in stabilizing perfluorooctyl bromide emulsions of certain concentrations than much more highly concentrated perfluorooctyl bromide/perfluorodecyl bromide emulsions without the significant problems experienced in higher concentrated emulsions such as longer organ retention times, formation of PFDB crystals, larger emulsion particles, manufacturing problems and inability of repeat dosing inherent with higher concentrations of perfluorodecyl bromide. |
priorityDate |
2006-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |