Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8778713427f3c00296d87dcb061a063e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-74 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4756 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate |
2012-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bacc31e23a3bdc84012f78d6afb50859 |
publicationDate |
2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8748131-B2 |
titleOfInvention |
Chimeric neuregulins and method of making and use thereof |
abstract |
Composition containing a chimeric neuregulin polypeptides and method of making such polypeptides are disclosed. The chimeric neuregulin comprises a first moiety of at least 10 amino acids, wherein the first moiety is derived from a first polypeptide; and a second moiety of at least 5 amino acids, wherein the second moiety is derived from a second polypeptide; wherein the first polypeptide is a neuregulin and the chimeric neuregulin exhibits an enhanced binding affinity to integrin, Erb 3, or Erb 4 comparing to that of the first neuregulin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015196621-A1 |
priorityDate |
2012-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |