| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ada68032e6c5599de33d868231aaa52d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06 |
| filingDate |
2012-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c04d7fbee72d40bcbd136616f46547
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_284111d8ac5221c26fb71a878b419cae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f20f69158c43db85f198bf9229053c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87de42d33eb970d5b0450af3c6c7e1e8 |
| publicationDate |
2014-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8729026-B2 |
| titleOfInvention |
Method for inhibiting autophagy of motor neurons |
| abstract |
A method for inhibiting the autophagy of motor neurons in a subject is provided. The method comprises administrating to the subject an effective amount of an active ingredient selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound and combinations thereof: n nwherein A is a C1-C5 alkyl optionally having one or more unsaturated bonds and optionally being substituted by one or more substituents selected from a group consisting of —OH, ═O and C1-C3 alkyl; X is H, —OH,n n nY is O or S and can optionally combine with A to form a five-membered ring; and R 1 is H or a substituted or unsubstituted C1-C20 alkyl, wherein one or more —CH 2 — of the C1-C20 alkyl are optionally being replaced by —NH— or —O—. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11013716-B2 |
| priorityDate |
2012-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |