| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87dbbaabbdd649f0c20f1fc3873987be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97407916ae9add6441777cadffdf50a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba715c40555c1c81e7adc9413b39ed7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79a1d1f77a58036edfaef56bb51b2bf5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30cf97a94ac50cf50e5670626be67e9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_365ca5d3c33140f724dd41c9997281c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c8fe906a97de920abf4effd3bccbc3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-06 |
| filingDate |
2006-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ec424d83e9981e601a7d7b58cc1e0a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ab65df276d8973b81033f8419900925
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb1a6159c740b7130b4161cc33814fbc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8381ea76101f04d3f1931643c02cef6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb46ee0822c8ccaae0ec438764f6453a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_356a6eec7320fdbeadea93f693f03f31 |
| publicationDate |
2014-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8716195-B2 |
| titleOfInvention |
Antibody ultrahumanization by predicted mature CDR blasting and cohort library generation and screening |
| abstract |
Methods and compositions directed to improved universal antibody libraries that rationally exploit human diversity information contained within reference antibody libraries, such as universal antibody libraries, are disclosed. The disclosed processes involve use of a query CDR sequence to guide incorporation of human antibody diversity present within the reference library into cohort libraries of the invention. Methods for making and screening such cohort libraries for isolating therapeutics suitable for treating disease are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10688181-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018085252-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10344096-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11179451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11312787-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9758591-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020028428-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11654193-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022153869-A1 |
| priorityDate |
2005-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |