Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a46560ed7935f87f1e0b780eb65ec33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21a837b6e77981109aa7871f1ca8c2fa |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 |
filingDate |
2011-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0113f9da641e9fe31d697dee9e74cc09 |
publicationDate |
2014-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8697651-B2 |
titleOfInvention |
Amyloid β fibrillogenesis-inhibiting peptide |
abstract |
The present invention provides a peptide which functions as a mimic peptide of an amyloid β peptide and is capable of inhibiting the fibrillogenesis of an amyloid β peptide. The present invention relates to an 8- to 30-amino acid residue peptide comprising an amino acid sequence represented by the following formula (I): X 1 -Asp-X 2 -X 3 -X 4 -Pro-X 5 -X 6 (SEQ ID NO: 28) (I), wherein X 1 represents a branched chain amino acid, and X 2 , X 3 , X 4 , X 5 , and X 6 are the same or different and each represents an α-amino acid, and to a pharmaceutical composition and an amyloid β fibrillogenesis inhibitor comprising the peptide. |
priorityDate |
2006-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |