Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68983dc3b68609c6ffee0ad74979e476 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5250dee3771d92ace924a3afa5556cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fe7763a38f97fdcd1a08f3cf45c46e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_179652ecd54a13a166b8990a779f5914 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ab3f3fdf2e55157dd50f6398dc272c1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
filingDate |
2008-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cfe9452acf6b34e0f78927b9c275a6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31cdff0f3b780a774a8e5d35b790529e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40f0981c02a619d59f0ec2d943c6af4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0307be06250d9b7b2362493a9f71685 |
publicationDate |
2014-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8673563-B2 |
titleOfInvention |
Amplification method of methylated or unmethylated nucleic acid |
abstract |
The object of the present invention is to provide a gene amplification method, wherein the method can amplify both methylated and unmethylated nucleic acids present in a biological sample, and further regulate the amplification ratio of the methylated and/or unmethylated nucleic acid as needed. Such objects can be solved by an amplification method using a nonspecific primer which can hybridize both with methylated and unmethylated nucleic acids and a specific primer which specifically hybridizes with either methylated or unmethylated nucleic acid, and further by an amplification method which can change the amplification ratio of methylated or unmethylated nucleic acid by changing the mixing rate of these primers. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9944984-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11414702-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11389779-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10351909-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9637785-B2 |
priorityDate |
2007-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |