http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8663604-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_138ea626ac0dc2e5782f3de6f2dfadbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22e3efbf1d99f55b950cfbf070aed8fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58f8b6337df8e5e7838e3810b1406a7d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4064 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-1495 |
| filingDate | 2008-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da4519e2b1709b2d8487143ac0c634aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b2e400701e5671728c7b64cf7c7fd62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18e52e689444becc72db0ce6ebf76165 |
| publicationDate | 2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8663604-B2 |
| titleOfInvention | Method for measuring neurotransmitters in vivo |
| abstract | A method is provided for in vivo detection of a biochemical substance in an animal by culturing neurofluocytes that stably express a receptor of the biochemical substances by transfecting cells with cDNA of the receptor and a tag that will emit a detectable energy in the presence of the biochemical substance, implanting the neurofluocyte into the animal's brain; and detecting the energy emission of the tag. In a first embodiment, the biochemical substance is a neurotransmitter, the tag is a fluophore, and the step of detecting includes forming an opening in the animal's skull and optically detecting fluorescent emissions using a two-photon laser scanning microscope. Multiple biochemical substances can be simultaneously detected by culturing neurofluocytes that express different receptors and have different fluophor tags that produce fluorescent signals at distinguishable wavelengths. |
| priorityDate | 2007-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 198.