http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8647877-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_530e9260809e47473d400d1225d62c4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34287c3dc4c9dee17fa20b7a502d2499 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8635f6edaed63c86f651769f88cf1210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ed4f00cf218e9c8dc089d18830f5149 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-101666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-22 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
filingDate | 2010-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a5fbd916102157a53395f52fd95420f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1404eea9e6deff9d330973194f02834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d522711d5a03f2d0939642d7630b733c |
publicationDate | 2014-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8647877-B2 |
titleOfInvention | Preparation and use of nucleated red blood cell simulating particles and hematology control mixtures |
abstract | The present disclosure provides a nucleated red blood cell simulating particle, which may be leukocytes bound to a fluorescent-staining inhibitor capable of stably binding to the nucleus or a nucleic acid in a cell so as to reduce the binding capacity of the particles to a fluorescent dye during their detection. The present disclosure also provides a method for preparing nucleated red blood cell simulating particles, including the following steps: (a) obtaining purified leukocytes; (b) suspending the leukocytes in a cell treatment solution containing a fluorescent-staining inhibitor which stably binds to the nucleus or a nucleic acid in a cell, and (c) washing the obtained product. The present disclosure also provides a hematology control mixture containing the nucleated red blood cell simulating particles. In addition, the present disclosure describes the use of the nucleated red blood cell simulating particles and the hematology control mixtures comprising the same, for the quality control of a blood cell analyzer. |
priorityDate | 2009-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.