Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ecb5749e03156851a2da9f618fe06c0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95cec123afa373b0980fecd8267c371a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d3317f029a4e8c102f29fb0b02a95fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_697bfe11b71d4cec00959316998e4468 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34 |
filingDate |
2009-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78c0fd90512ab0c17379d21782549c7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a129ff2abdce6e6e6d303de37d00f0d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf776c28c6b583c86e0c0f2a7ff52c1d |
publicationDate |
2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8637558-B2 |
titleOfInvention |
Thiazolidinedione derivative and use thereof |
abstract |
The present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and the uses thereof. More specifically, the present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and a pharmaceutical composition comprising the same. The novel thiazolidinedione derivatives of formula (I) according to the present invention can be effectively used for the prevention or treatment of cardiovascular disease, gastrointestinal disease and renal disease by inhibiting the activity of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) that decomposes prostaglandins as well as useful for the prevention of hair loss and the stimulation of hair growth, and osteogenic stimulation and wound healing. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11718589-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11690847-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10787425-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021032265-A1 |
priorityDate |
2008-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |