| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60ea72228076e815985f238c0eb149f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ff8b17b1230b3dd67367ce0a428f465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8a1a0665dedf21756dbefc001d747e1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56927
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4208 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-118 |
| filingDate |
2009-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_648427aecf69f3e9bbcf4e02e7a2fd8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3ebbc8fea900fd5b4e637981deed746 |
| publicationDate |
2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8637040-B2 |
| titleOfInvention |
Genus-wide chlamydial peptide vaccine antigens |
| abstract |
Peptides generated from a random library that are bound by a monoclonal antibody to Chlamydial glycolipid exoantigen (GLXA) and thus mimic this antigen are disclosed. Peptides that correspond to antigen-binding regions of an anti-idiotypic antibody (mAb2) specific for anti-GLXA antibody (Ab1) which act as molecular mimics of GLXA are also disclosed used as immunogens to induce broadly reactive genus-specific anti-chlamydial antibodies. These peptides and immunogenic DNA encoding the mAb2-like peptides, microparticle or nanoparticle formulations and other formulations of these peptides are disclosed as are methods for immunizing subjects to obtain genus-specific anti-chlamydial antibodies and to treat or prevent Chlamydia -associated or induced rheumatoid arthritis. |
| priorityDate |
2008-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |