http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8636894-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f1d8e0d546813f69a83cd630ec5bc48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b50382de55f1c85aa8b8889f0829564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48c1c389e4b9206dbccdd39818887033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85b959d2100bb308fcf773d125a37ab8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-26 |
| filingDate | 2009-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a770693fba270311b763d5cc06b6122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7620fe33c20e8b7a0950db7705d49b9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d622931aeae2d56a3ae7b6fd57b08ff |
| publicationDate | 2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8636894-B2 |
| titleOfInvention | Electrochemical determination of factor XA inhibitors |
| abstract | Methods and devices for determining factor Xa inhibitors, in particular heparins and fractionated or low-molecular-weight heparins, as well as direct factor Xa inhibitors in blood samples. The methods include contacting a blood sample with a detection reagent that contains at least one thrombin substrate having a peptide residue that can be cleaved by thrombin and is amidically bound via the carboxyl end to an electrogenic substance, and with a known amount of factor X reagent and an activator reagent which induces the conversion of factor X into factor Xa. Subsequently, in a second step, the amount or activity of the electrogenic substance that is cleaved from the thrombin substrate by the factor Xa-mediated thrombin activation and/or the time course thereof is determined as the measurement signal using electrochemical methods. In a third step, the amount of the factor Xa inhibitor in the sample of the blood to be analyzed or a measured quantity that correlates therewith, in particular a clotting time that correlates therewith, is determined on the basis of this measurement signal. |
| priorityDate | 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.