| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5aa75b06efae6b562e1b427113d271f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c6946793401973ea6d2418351f8720e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43f7af90780c65aefe8a81329bd25f53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29b03622d0484cd8b9431f3370edf11d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F7-00 |
| filingDate |
2008-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2663655c7b0ee513d159cc2a9c6bb5a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8541f04a94ae20aa7d22732809700e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24c5d32eed067779cb2155a526530ae4 |
| publicationDate |
2014-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8635029-B2 |
| titleOfInvention |
Systems and methods for biopolymer engineering |
| abstract |
Methods, computer systems, and computer program products for biopolymer engineering. A variant set for a biopolymer of interest is constructed by identifying, using a plurality of rules, a plurality of positions in the biopolymer of interest and, for each respective position in the plurality of positions, substitutions for the respective position. The plurality of positions and the substitutions for each respective position in the plurality of positions collectively define a biopolymer sequence space. A variant set comprising a plurality of variants of the biopolymer of interest is selected. A property of all or a portion of the variants in the variant set is measured. A sequence-activity relationship is modeled between (i) one or more substitutions at one or more positions of the biopolymer of interest represented by the variant set and (ii) the property measured for all or the portion of the variants in the variant set. The variant set is redefined to comprise variants that include substitutions in the plurality of positions that are selected based on a function of the sequence-activity relationship. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11043282-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015172082-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10770169-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3974524-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020033472-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11440953-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11355218-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013262406-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11216742-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434283-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3670660-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434285-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434284-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10916329-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9146945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10192641-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11424006-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11468355-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10991448-B2 |
| priorityDate |
2003-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |