Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_700ff9a01db2075489cb7ed87392dc28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d156230af998088e2dd486093e59b2da http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d96ad98ad42b4902a7c87aea5edefa8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43cb1139eeafbe246ea736ddf7df50b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41a639aa11b9b2f8063a3e6b8b22b557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51da70fed38d646cbfd145410f9ab24e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate |
2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_890bb22824f52fe59bfb6df20c2244b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53566dd122a736e96dc235d43b9b4362 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49208ad7e72efa018f31d6b7e550dbd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_350ad8ed63cfdf76a0466e8ba8a7c7df |
publicationDate |
2014-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8623375-B2 |
titleOfInvention |
Chimeric OspA genes, proteins, and methods of use thereof |
abstract |
The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies. The invention also provides methods for administering the chimeric OspA molecules to a subject in the prevention and treatment of Lyme disease or borreliosis. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9023367-B2 |
priorityDate |
2010-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |