| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32224257a4a15166a36b83aa711d107b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfcc83a125633c87ab4356bf0108dd37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7eb65841438fe0d890c9b35b1426245f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fac8f65c5c108a9df98f5220cb1b29ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ecd03acca85bf5758dc77fd44739c9bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1ebe20b44c108ba19e9febd88a8532a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y107-03003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96 |
| filingDate |
2011-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29829319794b0fdffc414126d909fd04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82af41321d82f63fd961d864c11d5f4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9ab6b18df61bb2150fadb9a09b12d8d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0c39cc01f65267516d0a989b502d58c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24ab5a573c9771a0d990e945b2ddb78a |
| publicationDate |
2013-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8618267-B2 |
| titleOfInvention |
PEG-urate oxidase conjugates and use thereof |
| abstract |
A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8921064-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10139399-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010323423-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11345899-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9017980-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11781119-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10815461-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10160958-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9885024-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10823727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11598767-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10731139-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926538-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9670467-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11639927-B2 |
| priorityDate |
1998-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |