| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd9192be493440dd6a9314bd2c9b5b5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_271e936506fac66b6169aa5df5428153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db278cf29786a2fc1c47f559ef01db93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80530469649bedd0a755d2f523209415 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-2525 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0695
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 |
| filingDate |
2008-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1408e51ba2f437b667d149616098f8d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a82c3f34a86be389e4bdbe1e02765e71 |
| publicationDate |
2013-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8614095-B2 |
| titleOfInvention |
Methods for identifying, purifying and enriching immature or stem cancer-initiating cells from tumors and use thereof |
| abstract |
Methods for the preparation of cell compositions based on fluorescence following excitation at wavelength of or about 488 nm and isolated cell compositions obtained therefrom wherein isolated cells exhibit (i) autofluorescence at or about 520 nm or (ii) absence of fluorescence at or about 520 nm and a positive shift in the fluorescence detected at >630 nm. These methods provide for enrichment of immature or stem cancer-initiating cells from tumors (notably, cancers of the central and peripheral nervous system and metastasis to the brain) and methods for screening antitumor agents using the same. Also provided are methods of detecting immature or stem cancer-initiating cells in a cell sample and methods of detecting recurrence of cancer stem cells in a cancer stem cell sample following treatment with an agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11319535-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10066269-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9862944-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014153209-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10457943-B2 |
| priorityDate |
2007-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |