Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cb03ff309c31e766cf428b88c1dd9a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f75cc61295b6c8882ca116d5fb634dca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9faf0ff03b05a5395781acdee289410 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54cea7118de1a11855eaae6c78ff82c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e45cde95d5a9f979ffdbc9e940715bc |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
filingDate |
2007-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_104bb47b579fd0211d66e3f79efa5f4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33625be23f454e6f212d6e22e08a4cc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_163c56fef2d28403b95a3bde792f6661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55295e4fe7afada5d9297ea36ffa2613 |
publicationDate |
2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8604044-B2 |
titleOfInvention |
Quinazoline based EGFR inhibitors containing a zinc binding moiety |
abstract |
The present invention relates to quinazoline containing zinc-binding moiety based derivatives of Formula (IV) below. n n n n n n n n n n These compounds have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and are useful in the treatment of EGFR-TK related diseases and disorders such as cancer. These compounds may further act as HDAC inhibitors. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9024024-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9890187-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9108929-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10640524-B2 |
priorityDate |
2006-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |