http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8586389-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da9df5d55904da06ef5fc7ebb1a43fbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8df23dcb7fec40fb30564b7369302da3 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5438 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 |
filingDate | 2006-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7b0d592cc2b1ed2a788a817af7563fd |
publicationDate | 2013-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8586389-B2 |
titleOfInvention | Ligand concentrating, liquid crystal biosensor system |
abstract | A method for detecting a ligand is provided. Antibodies to a predetermined ligand are attached to substrates. The substrates are superparamagnetic, dyed beads. The beads are exposed to an electromagnetic field to immobilize the beads. The beads are contacted with a sample and the antibodies are allowed to recognize and capture the ligand in the sample. The electromagnetic field is optionally removed. The beads are contacted with a liquid crystalline material and the light transmission properties of the liquid crystalline material are examined for alteration caused by the presence of aggregates of the beads and the ligand. A functional cassette for the detection of ligands comprises a pair of opposed, transparent substrates defining a space therebetween, a pair of transparent electrodes disposed on at least a portion of the opposed substrates on a side facing the opposing substrate and defining a primary detection area, and a secondary detection area adapted to capture aggregates of a ligand and ligand-recognizing antibodies attached to superparamagnetic, dyed beads. The detection areas are in fluid communication with each other. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11408854-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11382185-B2 |
priorityDate | 2005-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.