http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8575330-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b972d346ecc4ebf9831d912a0579e94e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_877f3d41c8f224d0a8074c6b615a8e4b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate | 2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7eeda209eb7ae6fef5e8ece0871e96b |
| publicationDate | 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8575330-B2 |
| titleOfInvention | MicroRNA-based short hairpin RNA for gene knockdown of NR1 subunit of N-methyl-D-aspartate receptor and its application on pharmaceutics |
| abstract | The present invention relates to a microRNA-based short hairpin RNA for gene silencing the genetic expression of NR1 subunit of N-methyl-D-aspartate receptor comprises a single strand RNA fragment comprising a first fragment, a second fragment and a connecting fragment, wherein the first fragment and the second fragment are complementary to each other, and are spaced and connected by the connecting fragment, with the connecting fragment being randomly arranged nucleotides, with the first fragment having a Drosha recognized cleavage site, a silencing site and a Dicer recognized cleavage site, with the Drosha recognized cleavage site and the Dicer recognized cleavage site being spaced and connected by the silencing site, with the silencing site encoding homologous nucleotides corresponding to NR1 subunit of subcutaneous N-methyl-D-aspartate receptor. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10751423-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11230708-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730826-B2 |
| priorityDate | 2012-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.