http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8575110-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a342602402f38dfcbd9a2972325f020 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7a4ec4a459b084c93b34cca01b0a0d3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 |
| filingDate | 2004-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7955c1a96cac32658ae642afc729df2f |
| publicationDate | 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8575110-B2 |
| titleOfInvention | Peptidic nanoparticles as drug delivery and antigen display systems |
| abstract | Described is a new type of nanoparticle using the concept of self-organization of a single continuous chain to form peptidic nanoparticles. In particular, nanoparticles of the invention consist of aggregates of a continuous chain comprising two peptidic oligomerization domains connected by a linker segment. Preferred are coiled-coil oligomerization domains with a contiguous pattern of hydrophobic residues spaced 3 and 4 residues apart. The invention provides a drug targeting and delivery system comprising a functionalized peptidic nanoparticle comprising ligands capable of binding a receptor and drugs, and a method of treating or diagnosing humans using such functionalized peptidic nanoparticles. The invention further provides an antigen display system to be used as efficient vaccines comprising a functionalized peptidic nanoparticle comprising an antigen, and a method of vaccinating humans or non-human animals using such functionalized peptidic nanoparticles. The invention also provides processes for making peptidic nanoparticles and functionalized peptidic nanoparticles, and monomeric building blocks suitable for forming such nanoparticles. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11213582-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188136-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10117956-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023108026-A2 |
| priorityDate | 2003-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 260.