http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8574844-B2

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filingDate 2007-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fafb695b3e69a402e05007fd865b81f
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publicationDate 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8574844-B2
titleOfInvention Quantitative real-time assay for Noroviruses and Enteroviruses with built in quality control standard
abstract A method is provided for reverse transcription-polymerase chain reaction (RT-PCR) accomplished by: a) amplifying a reverse transcribed cDNA in a mixture containing Norovirus Genogroup I and Norovirus Genogroup II primers and probes, in which the Norovirus primers and probes can distinguish between Genogroup I and Genogroup II viruses; b) quantifying virus; and c) normalizing data based on a universal internal RNA control. Optionally, the method may also include primers and probes for Enteroviruses. The present invention also provides a reaction mixture containing Norovirus Genogroup I and Norovirus Genogroup II primers and probes, in which the Norovirus primers and probes can distinguish between Genogroup I and Genogroup II viruses and universal internal RNA control primers and probes.
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