Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7b86c0e65ff0cf2731708808aab8441 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cce9b8198f2c9cf42e537467dfcd9f22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3d3303ad11c14284a71a7ca5e85f7eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb7537a9d1b22c0600ae5b9042c3a16b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 |
filingDate |
2010-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc2a9663c5536a8564febe3e6fa89b7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_882b732e1688b053ddb153e5874b12b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c940abddb83aba384f4108b750008745 |
publicationDate |
2013-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8569508-B2 |
titleOfInvention |
Synthetic method for montelukast sodium intermediate |
abstract |
A synthesis method for preparing Montelukast sodium intermediate 2-(2-(3-(2-(7-chloro-2-quinolyl)vinyl)phenyl-3-oxopropyl)phenyl) propanol is provided. In this method, the target compound is prepared by condensing the starting materials 7-chloroquinaldine and 3-cyanobenzaldehyde, and then reacting the resultant product with 2-(2-ortho-(2-haloethyl)-phenylpropyl)tetrahydropyrane ether. The present invention can easily obtain start materials and is applicable for mass production. |
priorityDate |
2009-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |