http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8569011-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b58f981963f6d55d627139e778c4ef7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_976b1c770a7ce5b7486a1f837e4c37aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f00183496ccda18bf9809d0cd226897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed71186ccaefbc3b6c10e65e4e6253ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6cc27730dd93e00071e6a069acaaf36 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate | 2012-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a4bc36fe78f9db7d38f2057ee349970 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_583359e67a46612100b052533205d239 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abd9fdf1ac4d30738a736d67fa9a0633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e52fe64783152dca4af98de643cda939 |
publicationDate | 2013-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8569011-B2 |
titleOfInvention | Fluorescent derivatives of polyamines, method for preparing same and applications thereof as diagnosis tools in the treatment of cancerous tumors |
abstract | The invention relates to novel fluorescent derivatives of polyamines having a benzoxadiazole group, to a method for preparing the same and to the use thereof as diagnosis tools for emphasising the polyamine transport system in cancerous cells in order to adapt the treatment thereof, and thus for selecting patients carrying such tumors in order to adapt their treatment. The derivatives are of the formula (I) or a pharmaceutically acceptable salt thereof, in which: R1 is one or more NO2 groups in position 4 or 6, or a SO2Ph, SO2NMe2, SO2NH2 or SO3H group; R2 is hydrogen, C1-6 alkyl, benzyl, a perfluoroalkyl group; the values of a, b, c range from 2 to 5 independently from each other and represent alkylene chains separating the amino groups, and the values of d and e can independently be 0 or 1. |
priorityDate | 2007-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 240.