| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acf741a300a5a458fe9f62962273b82d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fb34cf34084e57ded1e09a9713e9f3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bf05419a5f249ba6bd18e58370c5419
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_999f0f67fccd0c6deefa42df041081f8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C207-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-00 |
| filingDate |
2007-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ee980128f9ff03b5ebedb1f894e657
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_102c78d5ce7293becc29eefc612e8dc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_147d09e530856f65170f67dbd712d36d |
| publicationDate |
2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8563775-B2 |
| titleOfInvention |
Process for the preparation of (R)-(−)-3-(carbamoylmethyl)-5-methylhexanoic acid and of pregabalin and synthesis intermediates |
| abstract |
This invention relates to the preparation of (R)-(−)-3-(carbamoylmethyl)-5-methylhexanoic acid, in particular, the resolution of the acid racemate by means of salification with optically active amines and subsequent acidification to give the (R) enantiomer of the acid; this invention also concerns the salt intermediates formed with said amines and the conversion of said (R)-(−)-3-(carbamoylmethyl)-5-methylhexanoic acid into biologically active molecules such as pregabalin. |
| priorityDate |
2006-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |