Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad2cd796f8c4dcb425ddcc68707d3444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9557af56288e81940f1a4b728e3d87f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a94117124c90190316c0af47cde0b8e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc3692b763a286fa81ad3c32cb3054a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8edb89418e66cabd4e19f278f6ea3d86 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-50 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate |
2010-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9451318275ff512a792fc8ed2636b232 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e063000dccc332b848b14135e4da160 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90a38fbf28bf963bfc10f170898001cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17954b2abfc42555986608de5daa847e |
publicationDate |
2013-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8552170-B2 |
titleOfInvention |
Expression vector for establishing highly productive cell and the highly productive cell |
abstract |
The present invention provides an expression vector which is effective in an efficient establishment of transformed cells which express the aimed protein gene in a high level. An expression vector which has a cassette for expressing the drug selective marker gene containing mRNA destabilizing sequence, at least one element for stabilizing the gene expression and a cassette for expressing the gene of the aimed protein. Preferably, the mRNA destabilizing sequence is derived from AT-rich sequence existing in the 3′-untranslated region of cytokine, interleukin or proto-oncogene, and the element for stabilizing the gene expression is derived from Chinese hamster genome. |
priorityDate |
2009-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |