http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8551979-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c64bd4bcdfb515150a7b35ce3b5cad29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2874a198cb5a3593494d36246691632 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84581037cddeb620efaf08237364590d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-33 |
| filingDate | 2004-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af99e6c88420d79c87c1278fa1e2bff2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c50f777281137db092c2357f49c4716b |
| publicationDate | 2013-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8551979-B2 |
| titleOfInvention | Nonaqueous preparation for percutaneous absorption containing nonsteroidal anti-inflammatory analgesic |
| abstract | The present invention relates to nonaqueous preparation for percutaneous absorption prepared by laminating an adhesive layer comprising a nonsteroidal anti-inflammatory analgesic in an alkali metal salt form, and an inorganic acid which is strongly acidic compared with the nonsteroidal anti-inflammatory analgesic in a free form, together with a nonaqueous base, on a support. According to the present invention, drug-releasing characteristics and skin penetration in a nonaqueous preparation for percutaneous absorption can be improved because the addition of an inorganic acid in a nonaqueous base containing a drug in an alkali metal salt form leads to an improvement in the solubility of the drug in the base, and a good partitioning of the drug to skin surface. In addition, as the inorganic acid has no alcoholic hydroxy group in the structure, the inorganic acid does not react with the drug, therefore it causes no lowering in the stability of the drug by esterification. |
| priorityDate | 2004-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 283.