Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d55abcd3f3282ebe7a7dcb724b12d17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ba102ea9c02b6633d64bf09c5b89a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d51838da83f246cc7251b55456cfd096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7efb157f7e9b30660a911dec770dbeb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd8bcf8ee2a98d168e4ea3377b7c24fb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2009-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3a4d2f27a06832c760b46e7d268f31d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dff628e16c77c7437ab8e3575545815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5d98435f13e2ad6396e72661437275e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14bf8637702d6fa1051f2268d34e4527 |
publicationDate |
2013-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8545841-B2 |
titleOfInvention |
Methods and compositions for the treatment of cancers and pathogenic infections |
abstract |
The subject application provides small compounds that are able to suppress autophagy in various cells. These compounds are useful in augmenting the existing treatments of various cancers and microbial/parasitic infections. Thus, the subject application also provides methods of treating various types of cancers and microbial/parasitic infections. Also provided by the subject application are methods of suppressing the expansion of autophagosomes within cells or individuals and inhibiting the lipidation of autophagy-related protein 8 (Atg8). |
priorityDate |
2008-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |