http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8536339-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70055f3cedebe6e989784387209389a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d1615f5c7f3481aef7c3eee4d20aaf8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-02 |
| filingDate | 2011-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84ebf904580c82fa5296b87de9602ee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55ecb4905bd9d6b9e37a2f1f1198d724 |
| publicationDate | 2013-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8536339-B2 |
| titleOfInvention | AZA-indoles and related compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
| abstract | The present invention provides compounds are disclosed herein having the formula: n n n n n n n n n n n n Wherein n is 1 or 2; m is 0 or 1; p is 0, 1 or 2; R 1 is aryl, heteroaryl or alkyl; n R 2 is C 1-6 hydrocarbyl, alkylacyl or hydroxyalkyl; R 3 is aryl, heteroaryl, or alkyl; R 4 is H, OH, —O—(C 1-6 alkyl), —NH—(C 1-6 alkyl), or oxide; n R 5 is H, halogen, C 1-6 alkyl, O—(C 1-6 alkyl), aryl, heteroaryl, —C(═O)(C 1-6 alkyl), n substituted or un-substituted oxazolin-2-yl; n X═O, NH, —C(═O)— or —N═CH—; and n Each L is independently alkylene and carbonyl.n nTherapeutic methods, compositions, and medicaments related thereto are also disclosed. |
| priorityDate | 2008-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 441.