Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_379ad51616cbf16e84ec0b8e4004b697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_882a8922aa4d094380b51007bb9b17b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09a66193e0ed4f357c1ffae55ba9981e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99a4298f4801df63b494754aaa8b27ba |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44726 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-447 |
filingDate |
2011-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4ba7c79b53c621e744dfafb269f91cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06c435463728a7a870f8da17cb52ab34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24642af2bd3b1dbbf48b5dc42395af85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_963100efa71468f6a7d64d67cf7ca59b |
publicationDate |
2013-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8524061-B2 |
titleOfInvention |
On-chip hybridization coupled with ITP based purification for fast sequence specific identification |
abstract |
Isotachophoresis (ITP) can be employed to simultaneously focus the target and ligand of an assay into the same ITP focus zone. The target and ligand can bind to each other in the ITP focus zone, and then the resulting bound complex can be detected (e.g., by fluorescence). The sensitivity of this approach can be greatly increased by the enhanced concentration of both target and ligand that ITP provides in the focus zone. Since ITP can be performed quickly, the resulting assay is both rapid and sensitive. Markers of bacterial urinary tract infections have been experimentally detected at clinically relevant concentrations with this approach. MicroRNA sequences have also been profiled with this approach, which is clinically relevant because MicroRNA is expected to provide useful markers for disease. In one experiment, miR- 122 in human kidney and liver was detected and quantified. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9574232-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10822603-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10415030-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10787660-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10227634-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11041150-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11674132-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233441-B2 |
priorityDate |
2010-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |