Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab689140d566e7d9b1dc46e03b4576bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11acaea81bcb00d298d71a3c2366d3da http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dcb3f48d933cc97d3e887dec12c3d2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1852a61a0c30d1b02c5ae075f7b4c697 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D225-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-04 |
filingDate |
2011-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81e7f79a0887eca521a72499dce50f21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6515df09c92d41ce3a792f954c19bea8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eed8ef6ab87b6b5534bc10ade4ba6495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a653e87928b8e9deae338e7f1c73184f |
publicationDate |
2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8519122-B2 |
titleOfInvention |
Compositions and methods for modification of biomolecules |
abstract |
Provided are modified cycloalkyne compounds; and methods of use of such compounds in modifying biomolecules. Embodiments include a cycloaddition reaction that can be carried out under physiological conditions. The cycloaddition reaction involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo and in vitro. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE47539-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11149074-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9714288-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015191616-A1 |
priorityDate |
2010-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |