http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8518886-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4419151f58c7ae749f88e2065fdd6058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b537903e07982da81c8ea081da33597f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05 |
filingDate | 2011-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f580c90678f74f18aebbb002b00ea6d |
publicationDate | 2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8518886-B2 |
titleOfInvention | Cytoprotective thereapeutic agents for the prevention of reperfusion injury following ischemic stroke |
abstract | The present invention relates generally to the use of γ-glutamyl antioxidants, particularly γ-glutamyl-cysteine, as cytoprotective agents to prevent reperfusion injury (i.e., hemorrhagic transformation) of the blood-brain barrier during reperfusion following an ischemic stroke. The γ-glutamyl antioxidants can be used alone or used in combination with an agent which inhibits the reverse movement of Na/Ca exchange in the blood-brain barrier such as 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea methanesulphonate (KB-R7943). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9532961-B2 |
priorityDate | 2005-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.