| abstract |
The present invention relates to compounds of general formula (I): n n n n n n n n n n wherein: n R 1 represents:n halogen, CN or NO 2 ; n n R 2 represents:n hydrogen or halogen; n n n represents:n 1 or 2; n n R 3 represents:n phenyl substituted by one or more halogens or C 1 -C 6 alkyls; or a cyclohexyl;n nas well as the therapeutically-acceptable salts or solvates thereof.n n n n n These compounds are useful as protease-activated receptor-1 (PAR-1) antagonists, particularly in the treatment of thrombosis. |