http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8513000-B2

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filingDate 2010-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_561adedf6f7802b8138e438059d8672a
publicationDate 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8513000-B2
titleOfInvention High-throughput cell transfection device and methods of using thereof
abstract Transfecting biology cells with nucleic acid molecules (DNA, siRNA) is an essential prerequisite in elucidating how genes function in complex cellular context and how their activities could be modulated for therapeutic intervention. Traditionally studies are carried out on a low throughput gene-by-gene scale, which has created a huge bottleneck in functional genomic study and drug discovery. Development of high-throughput cell transfection technology will permit functional analysis of massive number of genes and how their activities could be modulated by chemical or biological entities inside cells. This invention describes design, construction of device and apparatus for high throughput effective cell transfection. Procedures and protocols for using the device and apparatus are also described in the application. Novel methods of using the device in cell-based assays are also disclosed.
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priorityDate 2006-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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