Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f46663eb655195a86f04a306181cd5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47daa062069893ed91551107052657db http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd149ada3d79f4bce9b80274444170f7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-775 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a20ced29e092d6f42abbdad6c5e7ab35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d51fb5dc720e1911e00b472095f6c49d |
publicationDate |
2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8512958-B2 |
titleOfInvention |
Methods of identifying agents that modulate mitochondrial function |
abstract |
The present invention provides isolated cells comprising a nucleic acid encoding a toxic form of apoE. The present invention further provides screening methods for identifying compounds that reduce apoE-induced impairment of mitochondrial integrity and/or function. The present invention further provides kits for use in carrying out a subject screening method. The present invention provides agents that reduce apoE-induced impairment of mitochondrial integrity and/or function; and use of such agents in the treatment of apoE-related disorders. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9102717-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013017251-A1 |
priorityDate |
2005-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |