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filingDate 2007-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_093fe19c166f8deb0bdaea640d803483
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publicationDate 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8512732-B2
titleOfInvention Method for producing bioactive composites
abstract An object of the present invention is to provide a method for producing bioactive composites having imparted thereto bioactivity, to thereby form and grow in vivo or in vitro a coating layer containing a calcium phosphate compound as the major component with a high adhesion strength on the surface of various types of porous substrates such as a porous shaped body comprising an organic polymer. The means for solving the problem is characterized by comprising at least (1) a step of immersing a porous substrate in a solution containing at least calcium ions and hydrogenphosphate ions, thereby distributing the solution to the inside of at least a part of the pores of the substrate, and (2) a step of depositing fine particles containing a calcium phosphate compound as the major component inside the pores into which the solution is introduced.
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